Validation of the CNS Penetration-Effectiveness rank for quantifying antiretroviral penetration into the central nervous system.
OBJECTIVETo consider whether or not penetration of a mix routine into the central nervous system (CNS), as estimated by the CNS Penetration-Effectiveness (CPE) rank, is related to decrease cerebrospinal fluid (CSF) viral load. METHODSData had been analyzed from 467 contributors who had been human immunodeficiency virus (HIV) seropositive and who reported antiretroviral (ARV) drug use.…