CRISPR / Cas9 method: The cutting edge technique
introduction This simple and fast method of changing genes has revolutionized the scientific world. The CRISPR / Cas9 method allows very fast and specific genome editing. This technique has already been used successfully in many model organisms (yeast, plant, zebrafish, Drosophila, nematode and mouse) and also works very well in human cell lines. As a result, it…
What is oxidative stress?
Oxidative stress in a living organism is a chemical state in which oxidative species overcome antioxidative systems due to an imbalance between the two parts. The oxidizing species, among which the free radicals stand out, perform important functions such as the elimination of pathogenic bacteria, the regulation of arterial pressure and the transmission of signals. If free…
Validation of the CNS Penetration-Effectiveness rank for quantifying antiretroviral penetration into the central nervous system.
OBJECTIVETo consider whether or not penetration of a mix routine into the central nervous system (CNS), as estimated by the CNS Penetration-Effectiveness (CPE) rank, is related to decrease cerebrospinal fluid (CSF) viral load. METHODSData had been analyzed from 467 contributors who had been human immunodeficiency virus (HIV) seropositive and who reported antiretroviral (ARV) drug use.…
Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers.
A pathological hallmark of Alzheimer’s illness is an accumulation of insoluble plaque containing the amyloid-beta peptide of 40-42 amino acid residues. Prefibrillar, soluble oligomers of amyloid-beta have been acknowledged to be early and key intermediates in Alzheimer’s-disease-related synaptic dysfunction. At nanomolar concentrations, soluble amyloid-beta oligomers block hippocampal long-term potentiation, trigger dendritic backbone retraction from pyramidal cells and…
Morphological Characteristic Regulation of Ligninolytic Enzyme Produced by Trametes polyzona.
A newly remoted white rot fungal pressure KU-RNW027 was recognized as Trametes polyzona, primarily based on an evaluation of its morphological traits and phylogenetic information. Aeration and fungal morphology have been essential components which drove pressure KU-RNW027 to secrete two completely different ligninolytic enzymes as manganese peroxidase (MnP) and laccase. Highest actions of MnP and laccase have…
Distributor office in Poland sees wild boar in the city!
With the lonckdown animals are coming int the city. Our distributor Gentaur in Sopot Poland has seen in front of the office wild boar. This is very dangerous, they can attack peopel but nobody come out today. Their office is near to Galleria Baltycka in Tricity between Sopot and Gdansk.
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Biotechnology
ChemHunting distributes life science tools and chemicals: 01. Cell culture Plasticwares02. Instruments03. Proteomics-related04. Immunology-related05. Filtration06. Cell culture media & reagents07. Molecular Biology-related